For all analyses, time, treatment method, and infusion purchase were being incorporated as in-subject matter components. The restricted maximal chance strategy was made use of with an autoregressive covariance construction. We employed this process of research for your VAS-anxiety, HDRS-17, and STAI-S. As Section of a sensitivity Investigation, we On top of that present success for all outcomes with data restricted to phase 1 in the trial on condition that some evidence of carryover consequences was present in the demo. This Investigation was identical to that outlined from the former paragraph.
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When proof of carryover consequences was existing, we limited Evaluation to section 1 information within the demo (approximately working day 14). We utilized SAS to construct more info a mixed-effects linear product with time and time-by-cure click here interaction as involved phrases from the design. The restricted maximal chance strategy was used with an autoregressive covariance structure.
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